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Fig. 5 | Cancer Cell International

Fig. 5

From: Long noncoding RNA ILF3-AS1 aggravates papillary thyroid carcinoma progression via regulating the miR-4306/PLAGL2 axis

Fig. 5

ILF3-AS1 expedites PTC progression via sponging miR-4306 to elevate PLAGL2 expression. a The expression of PLAGL2 was analyzed in response to pcDNA3.1/ PLAGL2. b, c The effects of miR-4306 and PLAGL2 on ILF3-AS1-mediated cell proliferation were demonstrated by colony formation assay and EdU assay. df The changes in apoptosis were observed in transfected PTC cells through TUNEL assay, flow cytometry analysis and caspase 3 activity detection. g, h The rescuing effects of miR-4306 inhibitor and pcDNA3.1/PLAGL2 on suppressed migratory and invasive capacities by sh-ILF3-AS1 were detected by wound healing assay and transwell assay. **P < 0.01

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