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Fig. 5 | Cancer Cell International

Fig. 5

From: Dendritic cells matured with recombinant human sperm associated antigen 9 (rhSPAG9) induce CD4+, CD8+ T cells and activate NK cells: a potential candidate molecule for immunotherapy in cervical cancer

Fig. 5

Characterization of SPDCs in the presence of chemotherapeutic agent cisplatin at three different doses (150, 200 and 400 µM/ml) (a) Bar diagram depicting cell death post cisplatin treatment (b) Overall proliferation of autologous PBMCs SPDCs in the presence or absence of cisplatin. c Phenotypic characterization of SPDCs in the presence or absence of cisplatin (d) Evaluation of migratory capacity of SPDCs with or without the cisplatin in culture medium (P = 0.01) (e) Overall proliferation of CD4+ (P = 0.194), CD8+ (P = 0.303) and NK cell response (P = 0.131) to SPDCs (± Cisplatin). Data shown is summary of experiments with three different patients (P10–P12)

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Cancer Cell International

ISSN: 1475-2867

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