The expression of STAT1 and MS4A4A after VWCE-overexpression treatment. a The expression of STAT1 and MS4A4A after VWCE-overexpression was analyzed by RT-PCR. b The correlation between VWCE-overexpression and STAT1 and MS4A4A in T47D and SK-BR-3 breast cancer cell lines was analyzed by western blotting. C Correlation between VWCE expression and immune infiltration level of Th1 and M2 macrophages in breast cancer. a The expression of VWCE in normal tissues (++), b The expression of VWCE in breast cancer tissues (+), c The expression level of STAT1 was high in breast cancer tissues (++), d The expression level of MS4A4A was relatively low in breast cancer tissues (+). The expression density of VWCE, STAT1, and MS4A4A in breast cancer tissue was quantitated by scoring staining intensity, including negative (−) and weak (+) staining, moderate (++) and strong (+++) staining, respectively.