Fig. 3
From: Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer
CircHECTD1 absence could reinforce DB-sensitivity in GC cells. AGS and HGC-27 cells were transfected with si-circHECTD1 or si-NC, severally. a Knockdown efficiency of si-circHECTD1 transfection in altering the level of circHECTD1 in the two GC cells. b, c MTT analysis for the IC50 of DB in treated cells. d The effect of circ-HECTD1 silencing on cell-cycle. e Flow cytometry analysis for the apoptosis of the two GC cells. f Relative levels of apoptosis-related proteins (Bcl-2 and Bax) in circHECTD2 deficient AGS and HGC-27 cells. The data represent the means ± SD of three independent assays. *P < 0.05