Skip to main content
Fig. 5 | Cancer Cell International

Fig. 5

From: Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer

Fig. 5

Circ-HECTD1 functioned its repressive effect on DB-sensitivity via miR-137 in AGS and HGC-27 cells. a QRT-PCR analysis for the level of miR-137 in AGS and HGC-27 cells with anti-miR-137 or anti-miR-NC transfection. bf AGS and HGC-27 cells with DB induction were introduced with anti-miR-NC, anti-miR-137, si-circHECTD1 + anti-miR-NC, or si-circHECTD1 + anti-miR-137, respectively. b, c The IC50 of DB in the two GC cells. d The influence of si-circHECTD1 or anti-miR-137 on cell cycle distribution. e The apoptotic ratio in si-circHECTD1 or anti-miR-137-mediated AGS and HGC-27 cells. f Relative levels of Bcl-2 and Bax in GC cells. The data represent the means ± SD of three independent experiments. *P < 0.05

Back to article page