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Fig. 6 | Cancer Cell International

Fig. 6

From: Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer

Fig. 6

PBX3 was directly targeted by miR-137. a Complementary binding sites between miR-137 and PBX3 were predicted by Targetscan software. b The luciferase activities of AGS and HGC-27 cells with WT-PBX3 or MUT-PBX3 and miR-137 or miR-NC co-transfection. c RIP analysis for the validation of the relationship between miR-137 and PBX3. d RNA pull down assay for PBX3 level in cells with miR-NC probe or miR-137 probe incubated. ef The impact of miR-137 depletion on the level of PBX3 in GC cells. g The correlation between miR-137 and PBX3 in 25 cases of GC specimens. The data from the three different assays were presented as means ± SD. *P < 0.05

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