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Fig. 7 | Cancer Cell International

Fig. 7

From: Circular RNA circHECTD1 prevents Diosbulbin-B-sensitivity via miR-137/PBX3 axis in gastric cancer

Fig. 7

MiR-137 modulated DB-resistance by targeting PBX3 in the two GC cells. ab The knockdown efficiency of si-PBX3 transfection in PBX3 level. cg si-NC, si-PBX3, anti-miR-137 + si-NC, or anti-miR-137 + si-PBX3 was transfected into AGS and HGC-27 cells with DB exposure. cd MTT analysis for the IC50 values (µM) of DB in the two GC cells. ef Flow cytometry analysis for e cell-cycle and f cell apoptosis in vitro. g Relative levels of Bcl-2 and Bax in treated AGS and HGC-27 cells. The data of the three different tests were exhibited as means ± SD. *P < 0.05

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