CircRNA_100290 promotes GC cell proliferation and invasion via the miR-29b-3p/ITGA11 axis and is regulated by EIF4A3

Table 2 Relevance analysis between expression of ITGA11 and clinicopathological characteristics in GC patients from TCGA database

Characteristics	N	Expression of ITGA11		χ2	P
Characteristics	N	Low	High	χ2	P
Gender	375			2.161	0.142
Male	241	114	127 (52.7%)
Female	134	74	60 (44.8%)
Age (years)	371			0.61	0.435
< 65	155	81	74 (47.7%)
≥ 65	216	104	112 (51.9%)
Histological grade	366			1.921	0.166
G1 + G2	147	80	67 (45.6%)
G3	219	103	116 (53.0%)
Lauren’s types^a	229			7.323	0.026
Intestinal	157	77	80 (51.0%)
Diffuse	55	18	37 (67.3%)
Mixed	17	4	13(76.5)
Depth of invasion	367			22.669	0.000
T1	19	18	1 (5.30%)
T2	80	46	34 (42.5%)
T3	168	85	83 (49.4%)
T4	100	38	62 (62.0%)
Ln metastasis	357			5.471	0.14
N0	111	64	47 (42.3%)
N1	97	52	45 (46.4%)
N2	75	33	42 (56.0%)
N3	74	32	42 (56.8%)
Distant metastasis	355			1.169	0.28
M0	330	169	161 (48.8%)
M1	25	10	15 (60.0%)
TNM Staging	352			13.737	0.003
I	53	39	14 (26.4%)
II	111	54	57 (51.4%)
III	150	69	81 (54.0%)
IV	38	16	22 (57.9%)

ISSN: 1475-2867