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Fig. 7 | Cancer Cell International

Fig. 7

From: Elevated expression of LPCAT1 predicts a poor prognosis and is correlated with the tumour microenvironment in endometrial cancer

Fig. 7

Correlation of the proportion of TICs in UCEC samples, and association of TICs proportion and typical ICGs with LPCAT1 expression. a Barplot showing the proportion of 22 types of TICs in the UCEC tumour samples. The column names of the barplot are the sample IDs. b Heatmap showing the correlation between 22 kinds of TICs, the p-value in each tiny box indicates the correlation between two cells. Person’s correlation coefficient was used for statistical significance test. c Violin plot showing the differentiation ratio of 28 kinds of immune cells between UCEC tumour samples with high or low LPCAT1 expression relative to the median of LPCAT1 expression level, and the Wilcoxon rank sum was used as the statistical significance test. d Scatter plot showing the correlation of 19 TIC proportions with the LPCAT1 expression (p < 0.05). The red line in each plot was the fitted curve of linear model indicating the immune cells proportion tropism along with LPCAT1 expression, and the Person correlation coefficient was applied for statistical significance test. e Venn plot displaying fifteen kinds of TICs correlated with LPCAT1 expression codetermined by correlation and difference tests displayed in violin and scatter plots, respectively. f Differential expression of ICGs between the LPCAT1 high-expression group and LPCAT1 low-expression group. *p < 0.05, **p < 0.01, ***p < 0.001

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