Skip to main content
Fig. 6 | Cancer Cell International

Fig. 6

From: A novel autophagy-related genes prognostic risk model and validation of autophagy-related oncogene VPS35 in breast cancer

Fig. 6

VPS35 knockdown inhibits breast cancer cell proliferation, migration, invasion and induces autophagy. a VPS35 expression is substantially suppressed in shVPS35 1#, shVPS35 2#, and shVPS35 3# sublines. b CCK8 assay upon VPS35 knockdown in MDA-MB-231 and SK-BR-3. c Colony formation assay upon VPS35 knockdown in MDA-MB-231. d Transwell migration/invasion assays upon VPS35 knockdown in MDA-MB-231. e Knockdown of VPS35 induced the transition of the LC3BI to LC3BII. f The track of LC3 expression upon VPS35 knockdown by autophagy flux assay in HEK293. Original magnification was × 600. * p < 0.05, ** p < 0.01, *** p < 0.001

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us