Table 1 Clinical pathological parameters of patients with breast cancer from TCGA
Feature | N (539) | % |
|---|---|---|
Age (years) | ||
> 60 | 227 | 42.1 |
≤ 60 | 312 | 57.9 |
T classification | ||
T1 (< 2 cm) | 147 | 27.3 |
T2 (2–5 cm) | 323 | 59.9 |
T3 (≥ 5 cm) | 55 | 10.2 |
T4 (chest wall and/or skin invasion) | 14 | 2.6 |
N classification (pN) | ||
N0 (no metastasis) | 259 | 48.1 |
N1 (1–3 metastasis) | 178 | 33 |
N2 (4–9 metastasis) | 64 | 11.9 |
N3 (≥ 10 metastasis) | 38 | 7 |
M classification | ||
M0 (no distant metastasis) | 528 | 98 |
M1 (distant metastasis) | 11 | 2 |
TNM stage | ||
I | 96 | 17.8 |
II | 318 | 59 |
III | 114 | 21.2 |
IV | 11 | 2 |
ER | ||
Negative | 127 | 23.6 |
Positive | 412 | 76.4 |
PR | ||
Negative | 175 | 32.5 |
Positive | 364 | 67.5 |
HER2 | ||
Negative | 440 | 81.6 |
Positive | 99 | 18.4 |
Molecular subtypes | ||
HER2 amplification | 92 | 17.1 |
Luminal A/B | 419 | 77.7 |
TNBC | 28 | 5.2 |