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Table 1 Causes of MMR perturbation at the protein expression level in breast cancer according to the hormone receptor status

From: Mismatch repair-deficient hormone receptor-positive breast cancers: Biology and pathological characterization

  HR+ (n = 69) HR− (n = 12)
MutS alone, n (%)   
MSH2 17 (25) 3 (25)
MSH6 4 (6) 0
Both proteins 6 (9) 0
MutL alone, n (%)   
MLH1 10 (15) 1 (8)
PMS2 3 (4) 0
Both proteins 2 (3) 1 (8)
MutS + MutL, n (%)   
MutS + MLH1 4 (6) 0
MutL + MSH2 2 (3) 1 (8)
MutL + MSH6 1 (2) 0
MSH2 + MLH1 8 (12) 4 (3)
MSH2 + PMS2 1 (2) 1 (8)
MSH6 + MLH1 2 (3) 0
MSH6 + PMS2 1 (2) 0
All proteins 8 (12) 1 (8)