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Table 2 Therapeutic effects influenced by dynamic cell communications

From: Using dynamic cell communication improves treatment strategies of breast cancer

Treatment

Changes in effects

References

Surgical removal of the primary cancer

Eliminate inhibitions from primary tumors to micro-metastatic foci

[78]

Target of ER

Mutations in ER or transformations from ER+ to ER−

[55]

Doxorubicin

Maximum-tolerated dose of doxorubicin promotes the proliferation of cancer cells

[99]

Microwave ablation combined with OK-432

Change the ratio of Th1 to Th2 cells to reduce reoccurrence of cancer

[113]

Target of metastatic cancer

Heterogeneity between the primary and metastatic breast cancer

[93]

Neoadjuvant versus adjuvant chemotherapy

Patients receiving neoadjuvant chemotherapy have a higher local recurrence rate

[114]