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Table 2 Therapeutic effects influenced by dynamic cell communications

From: Using dynamic cell communication improves treatment strategies of breast cancer

Treatment Changes in effects References
Surgical removal of the primary cancer Eliminate inhibitions from primary tumors to micro-metastatic foci [78]
Target of ER Mutations in ER or transformations from ER+ to ER [55]
Doxorubicin Maximum-tolerated dose of doxorubicin promotes the proliferation of cancer cells [99]
Microwave ablation combined with OK-432 Change the ratio of Th1 to Th2 cells to reduce reoccurrence of cancer [113]
Target of metastatic cancer Heterogeneity between the primary and metastatic breast cancer [93]
Neoadjuvant versus adjuvant chemotherapy Patients receiving neoadjuvant chemotherapy have a higher local recurrence rate [114]