Fig. 1From: Overcoming the UCB HSCs –Derived NK cells Dysfunction through Harnessing RAS/MAPK, IGF-1R and TGF-β Signaling PathwaysConceptual schema of the generation and activation of NK cells. In the present study, RAS/MAPK, PI3K/AKT, JAK/STAT pathways (involved in NK cells differentiation and activation) and TGF-β pathway (involved in NK cells dysfunction) were induced and inhibited respectivelyBack to article page