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Fig. 5 | Cancer Cell International

Fig. 5

From: Circular RNA circ_0006168 enhances Taxol resistance in esophageal squamous cell carcinoma by regulating miR-194-5p/JMJD1C axis

Fig. 5

Circ_0006168 regulated Taxol resistance by affecting JMJD1C expression. Eca109/Taxol and KYSE150/Taxol cells were transfected with si-control, si-circ_0006168, si-circ_0006168 + pcDNA, or si-circ_0006168 + pcDNA-JMJD1C. A Western blot assay was used to analyze the protein abundance of JMJD1C. B, C Cell viability and IC50 value of Taxol were determined by CCK-8 analysis. D, E CCK-8 assay and colony formation assay were employed to evaluate cell proliferation. F, G Cell migration and invasion abilities were assessed by transwell assay. H Flow cytometry analysis was applied to detect cell apoptosis. *P < 0.05, **P < 0.001, ***P < 0.0001

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Cancer Cell International

ISSN: 1475-2867

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