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Fig. 3 | Cancer Cell International

Fig. 3

From: YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways

Fig. 3

YWHAE affects cell invasion, migration, and epithelial–mesenchymal transition in ovarian cancer. a, b YWHAE expression in ovarian cancer cell lines. c, d Western blot analysis of YWHAE over-expression, mock-transduced, and untransduced OVCAR3 and A2780 cells. e, f Western blot of YWHAE knock-down, mock-transduced, and untransduced CAOV3 and ES2 cells. g, h Effects of high YWHAE expression on the invasion of ovarian cancer in OVCAR3 and A2780 cells. i, j Effects of low YWHAE expression on the invasion of ovarian cancer in CAOV3 and ES2 cells. k, l Effects of high YWHAE expression on the migration of ovarian cancer in OVCAR3 and A2780 cells. m, n Effects of low YWHAE expression on the migration of ovarian cancer in CAOV3 and ES2 cells

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