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Table 2 Relationships between the expression of YWHAE and clinicopathological parameters

From: YWHAE as an HE4 interacting protein can influence the malignant behaviour of ovarian cancer by regulating the PI3K/AKT and MAPK pathways

Groups

Cases

Low

High

Positive rate (%)

P-value

High expression rate (%)

P-value

(−)

(+)

(++)

(+++)

Age at diagnosis

 < 55

54

4

13

18

19

92.59

P = 0.066

68.52

P = 0.651

 ≥ 55

51

0

14

18

19

100.00

72.55

Pathological type

 Serous

71

2

14

28

27

97.18

P = 0.222

77.46

P = 0.073

 Mucinous

7

1

3

2

1

85.71

42.86

 Endometrioid

19

1

6

4

8

94.73

63.16

 Clear cell carcinoma

8

0

4

2

2

100.00

50.00

FIGO stage

 I–II

44

3

16

12

13

93.18

P = 0.307

56.82

P = 0.009

 III–IV

61

1

11

24

25

98.36

80.33

Differentiation

 Well and moderate

51

3

13

12

23

94.12

P = 0.354

68.63

P = 0.687

 Poor

54

1

14

24

15

98.15

72.22

Lymphatic metastasis

 No

64

4

18

22

20

93.75

P = 0.310

65.63

P = 0.214

 Yes

28

0

6

10

12

100.00

78.57

 Unknowna

13

0

3

4

6

100.00

76.92

  1. a13 patients without lymphadenectomy