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Fig. 3 | Cancer Cell International

Fig. 3

From: Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

Fig. 3

GOLT1B promotes metastasis of colorectal cancer in vivo. a GOLT1B stable overexpression was verified by qPCR and western blot. b The migration and invasion ability of HCT116 cells stablely transfected with control vector or GOLT1B were determined by transwell assays in vitro. c The average bioluminescence imaging signals in mice bearing liver metastatic burden was determined by IVIS imaging (HCT116Vector vs. HCT116GOLT1B, n = 8). d Body weight curves of mice in two groups. e Representative images of metastatic foci (pointed out with red arrow) in mice liver. f The number of liver metastatic foci in control vector and GOLT1B group. g IHC staining of GOLT1B and H&E staining in liver metastatic loci

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Cancer Cell International

ISSN: 1475-2867

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