|
Variables
|
Univariate analysis
|
Multivariate analysis
|
|---|
| |
HR (95%CI)
|
P value
|
HR (95%CI)
|
P value
|
|---|
|
Gender (male vs female)
|
0.881 (0.526–1.477)
|
0.632
| | |
|
Age (≥ 67 vs < 67)
|
1.929 (1.135–3.281)
|
0.015*
|
1.318 (0.749–2.318)
|
0.338
|
|
pT status (T3-T4 vs T1-T2)
|
7.270 (2.635–20.057)
|
< 0.001***
|
3.004 (1.004–8.989)
|
0.049*
|
|
pN status (N1-N2 vs N0)
|
7.164 (4.201–12.217)
|
< 0.0001****
|
2.690 (1.429–5.065)
|
0.0022**
|
|
pM status (M1 vs M0)
|
15.165 (8.692–26.456)
|
< 0.0001****
|
6.337 (3.387–11.859)
|
< 0.0001****
|
|
Histological grade (G3 vs G1-G2)
|
0.594 (0.335–1.054)
|
0.075
|
1.144 (0.620–2.109)
|
0.667
|
|
Recurrence (YES vs NO)
|
1.752 (0.701–4.382)
|
0.230
| | |
|
GOLT1B expression (High vs Low)
|
5.089 (2.189–11.834)
|
< 0.001***
|
2.520 (1.034–6.142)
|
0.042*
|
- Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001
