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Table 2 Univariate and multivariate analysis of different parameters for overall survival in CRC patients

From: Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

Variables

Univariate analysis

Multivariate analysis

 

HR (95%CI)

P value

HR (95%CI)

P value

Gender (male vs female)

0.881 (0.526–1.477)

0.632

  

Age (≥ 67 vs < 67)

1.929 (1.135–3.281)

0.015*

1.318 (0.749–2.318)

0.338

pT status (T3-T4 vs T1-T2)

7.270 (2.635–20.057)

< 0.001***

3.004 (1.004–8.989)

0.049*

pN status (N1-N2 vs N0)

7.164 (4.201–12.217)

< 0.0001****

2.690 (1.429–5.065)

0.0022**

pM status (M1 vs M0)

15.165 (8.692–26.456)

< 0.0001****

6.337 (3.387–11.859)

 < 0.0001****

Histological grade (G3 vs G1-G2)

0.594 (0.335–1.054)

0.075

1.144 (0.620–2.109)

0.667

Recurrence (YES vs NO)

1.752 (0.701–4.382)

0.230

  

GOLT1B expression (High vs Low)

5.089 (2.189–11.834)

< 0.001***

2.520 (1.034–6.142)

0.042*

  1. Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001
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Cancer Cell International

ISSN: 1475-2867

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