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Table 3 Univariate and multivariate analysis of different parameters for progression-free survival in CRC patients

From: Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

Variables

Univariate analysis

Multivariate analysis

 

HR (95%CI)

P value

HR (95%CI)

P value

Gender (male vs female)

1.075 (0.569–1.519)

0.772

  

Age (> 67 vs ≤ 67)

1.452 (0.889–2.372)

0.137

  

pT status (T3-T4 vs T1-T2)

3.708 (1.770–7.769)

< 0.001***

1.736 (0.767–3.928)

0.186

pN status (N1-N2 vs N0)

5.456 (3.329–8.941)

< 0.0001****

2.536 (1.420–4.530)

< 0.0017**

pM status (M1 vs M0)

10.387 (6.121–17.627)

< 0.0001****

4.244 (2.385–7.552)

< 0.0001****

Histological grade (G3 vs G1-G2)

0.773 (0.460–1.297)

0.329

  

Recurrence (YES vs NO)

4.149 (2.043–8.425)

< 0.0001****

2.363 (1.155–4.837)

0.019*

GOLT1B expression (High vs Low)

4.092 (1.953–8.573)

< 0.001***

2.194 (1.002–4.802)

0.049*

  1. Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001