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Table 3 Univariate and multivariate analysis of different parameters for progression-free survival in CRC patients

From: Vesicle transporter GOLT1B mediates the cell membrane localization of DVL2 and PD-L2 and promotes colorectal cancer metastasis

Variables Univariate analysis Multivariate analysis
  HR (95%CI) P value HR (95%CI) P value
Gender (male vs female) 1.075 (0.569–1.519) 0.772   
Age (> 67 vs ≤ 67) 1.452 (0.889–2.372) 0.137   
pT status (T3-T4 vs T1-T2) 3.708 (1.770–7.769) < 0.001*** 1.736 (0.767–3.928) 0.186
pN status (N1-N2 vs N0) 5.456 (3.329–8.941) < 0.0001**** 2.536 (1.420–4.530) < 0.0017**
pM status (M1 vs M0) 10.387 (6.121–17.627) < 0.0001**** 4.244 (2.385–7.552) < 0.0001****
Histological grade (G3 vs G1-G2) 0.773 (0.460–1.297) 0.329   
Recurrence (YES vs NO) 4.149 (2.043–8.425) < 0.0001**** 2.363 (1.155–4.837) 0.019*
GOLT1B expression (High vs Low) 4.092 (1.953–8.573) < 0.001*** 2.194 (1.002–4.802) 0.049*
  1. Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001