|
Variables
|
Univariate analysis
|
Multivariate analysis
|
|---|
| |
HR (95%CI)
|
P value
|
HR (95%CI)
|
P value
|
|---|
|
Gender (male vs female)
|
1.075 (0.569–1.519)
|
0.772
| | |
|
Age (> 67 vs ≤ 67)
|
1.452 (0.889–2.372)
|
0.137
| | |
|
pT status (T3-T4 vs T1-T2)
|
3.708 (1.770–7.769)
|
< 0.001***
|
1.736 (0.767–3.928)
|
0.186
|
|
pN status (N1-N2 vs N0)
|
5.456 (3.329–8.941)
|
< 0.0001****
|
2.536 (1.420–4.530)
|
< 0.0017**
|
|
pM status (M1 vs M0)
|
10.387 (6.121–17.627)
|
< 0.0001****
|
4.244 (2.385–7.552)
|
< 0.0001****
|
|
Histological grade (G3 vs G1-G2)
|
0.773 (0.460–1.297)
|
0.329
| | |
|
Recurrence (YES vs NO)
|
4.149 (2.043–8.425)
|
< 0.0001****
|
2.363 (1.155–4.837)
|
0.019*
|
|
GOLT1B expression (High vs Low)
|
4.092 (1.953–8.573)
|
< 0.001***
|
2.194 (1.002–4.802)
|
0.049*
|
- Univariate and multivariate Cox proportional hazards regression were used to calculate Hazard ratio (HR), 95% confidence intervals (95% CI) and p values in SPSS 24.0. Low GOLT1B is defined as IHC score < 5 and High GOLT1B is defined as IHC score ≥ 5. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001
