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Fig. 4 | Cancer Cell International

Fig. 4

From: IFI35 is involved in the regulation of the radiosensitivity of colorectal cancer cells

Fig. 4

Effect of IFI35 on X-ray irradiation and reactive oxygen species and mitochondrial membrane potential of colorectal cancer cells. A Flow cytometry detection of the effect of IFI35 on reactive oxygen species (ROS) of colorectal cancer cells. The bar graphs show the production of ROS. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. B Mitochondrial membrane potential of colorectal cancer cells determined by JC-1 immunofluorescence. Ad-NC: adenovirus, negative control; Ad-IRF1, adenovirus for IRF1 overexpression; sh: short hairpin RNA for the downregulation of IRF1 or IFI35. shNC: negative control short hairpin RNA

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