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Table 1 Area under the curve of candidate biomarkers in distinguishing controls from GC patients

From: A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer

Gene

TCGA

GSE54129

AUC

Std. error

P-value

95% CI

AUC

Std. error

P-value

95% CI

Lower

Upper

Lower

Upper

AGT

0.717

0.040

 < 0.001

0.639

0.795

0.617

0.049

0.089

0.522

0.713

SERPINH1

0.913

0.020

 < 0.001

0.873

0.952

0.957

0.016

 < 0.001

0.925

0.989

ATR

0.908

0.026

 < 0.001

0.856

0.959

0.328

0.049

0.013

0.232

0.425

WNT2

0.946

0.014

 < 0.001

0.919

0.973

0.991

0.007

 < 0.001

0.978

1.000

LIPG

0.829

0.032

 < 0.001

0.766

0.892

0.890

0.039

 < 0.001

0.813

0.966

PLAU

0.892

0.018

 < 0.001

0.858

0.927

0.913

0.025

 < 0.001

0.864

0.962

COL1A1

0.930

0.015

 < 0.001

0.901

0.959

0.972

0.014

 < 0.001

0.945

0.999

SERPINB5

0.661

0.059

0.003

0.545

0.776

0.403

0.057

0.159

0.292

0.514

MMP7

0.787

0.038

 < 0.001

0.713

0.861

0.733

0.047

0.001

0.641

0.826

WNT5A

0.719

0.057

 < 0.001

0.607

0.831

0.550

0.051

0.465

0.451

0.650

MXRA5

0.823

0.025

 < 0.001

0.775

0.871

0.782

0.040

 < 0.001

0.703

0.860

CTSC

0.706

0.050

 < 0.001

0.609

0.804

0.545

0.058

0.512

0.432

0.658

HPSE

0.750

0.053

 < 0.001

0.646

0.853

0.469

0.060

0.652

0.351

0.587

CXCL16

0.796

0.037

 < 0.001

0.723

0.870

0.462

0.054

0.582

0.356

0.568

CXCL1

0.830

0.035

 < 0.001

0.762

0.898

0.783

0.046

 < 0.001

0.693

0.874

COL11A1

0.924

0.016

 < 0.001

0.893

0.955

0.911

0.025

 < 0.001

0.862

0.959

  1. AUC area under curve, Std. standard, CI confidence interval