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Table 3 Univariate and multivariate Cox regression analyses in GSE15459 and TCGA dataset

From: A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer

Variables

Univariate analyses

Multivariate analyses

HR (95% CI)

P-value

HR (95% CI)

P-value

GSE15459

 Three gene risk score

2.470 (1.620–3.767)

 < 0.001

1.806 (1.178–2.771)

0.007

 Gender

0.713 (0.462–1.101)

0.127

  

 Age

0.966 (0.645–1.445)

0.865

  

 Stage

6.520 (3.597–11.816)

 < 0.001

5.684 (3.110–10.389)

 < 0.001

TCGA

 Three gene risk score

1.446 (1.034–2.022)

0.031

1.296 (0.918–1.829)

0.141

 Gender

0.917 (0.644–1.306)

0.630

  

 Age

0.933 (0.669–1.301)

0.682

  

 Tumor invasion

1.880 (1.218–2.902)

0.004

2.218 (1.405–3.500)

0.001

 Lymph node invasion

1.727 (1.145–2.605)

0.009

1.482 (0.884–2.485)

0.135

 Metastasis

1.931 (1.067–3.496)

0.030

1.893 (1.021–3.508)

0.043

 Pathological stage

1.518 (1.082–2.128)

0.016

1.196 (0.768–1.861)

0.428

 Histological grade

1.313 (0.924–1.866)

0.129

  
  1. HR hazard ratio, CI confidence interval