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Table 3 Univariate and multivariate Cox regression analyses in GSE15459 and TCGA dataset

From: A novel strategy to identify candidate diagnostic and prognostic biomarkers for gastric cancer

Variables Univariate analyses Multivariate analyses
HR (95% CI) P-value HR (95% CI) P-value
GSE15459
 Three gene risk score 2.470 (1.620–3.767)  < 0.001 1.806 (1.178–2.771) 0.007
 Gender 0.713 (0.462–1.101) 0.127   
 Age 0.966 (0.645–1.445) 0.865   
 Stage 6.520 (3.597–11.816)  < 0.001 5.684 (3.110–10.389)  < 0.001
TCGA
 Three gene risk score 1.446 (1.034–2.022) 0.031 1.296 (0.918–1.829) 0.141
 Gender 0.917 (0.644–1.306) 0.630   
 Age 0.933 (0.669–1.301) 0.682   
 Tumor invasion 1.880 (1.218–2.902) 0.004 2.218 (1.405–3.500) 0.001
 Lymph node invasion 1.727 (1.145–2.605) 0.009 1.482 (0.884–2.485) 0.135
 Metastasis 1.931 (1.067–3.496) 0.030 1.893 (1.021–3.508) 0.043
 Pathological stage 1.518 (1.082–2.128) 0.016 1.196 (0.768–1.861) 0.428
 Histological grade 1.313 (0.924–1.866) 0.129   
  1. HR hazard ratio, CI confidence interval