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Table 2 Univariate COX and multivariate COX regression analyses of potential prognostic factors related to MM-induced myocardial damage

From: Exosomal circRNA as a novel potential therapeutic target for multiple myeloma-related myocardial damage

Prognostic factor

Cumulative response rate of PN

Univariate Cox regression analysis

Multivariate Cox regression analysis

RR (95% CI)

P value

RR (95%CI)

P value

HGB ≥ 100 g/L

8.604 (1.038–71.335)

0.013

–

–

M% < 47.65%

1.794 (0.424–7.584)

0.419

–

–

D-S stage

0.398 (0.162–0.980)

0.072

–

–

NYHA grade

58.054 (0.248–13,597.283)

0.001

–

–

EF < 50%

0.86 (0.760–0.980)

0.005

–

–

NTproBNP ≥ 1800

58.054 (0.248–13,597.283)

0.001

–

–

circRNA < 2.18

107.551 (0.318–36,420.553)

0.000

107.551 (0.318–36,420.553)

0.000

  1. *P < 0.1 was considered to be statistically significant in univariate Cox regression analysis, and P < 0.05 was considered to be statistically significant in multivariate Cox regression analysis