Fig. 7From: Circ_0001721 enhances doxorubicin resistance and promotes tumorigenesis in osteosarcoma through miR-758/TCF4 axisDepletion of circ_0001721 hindered tumor growth in vivo. MG63/DXR cells introduced with sh-NC or sh-circ_0001721 were subcutaneously inoculated into nude mice. A After injection, tumor volume was measured once a week. B Mice were sacrificed after 28 days, and the xenografts were weighed. C–E The levels of circ_0001721, miR-758 and TCF4 were detected by qRT-PCR or western blot. F The protein levels of TAM, Survivin, caspase3 and caspase9 were examined using western blot analysis. *P < 0.05Back to article page