Fig. 1

NEAT1 expression is increased and let-7 g is decreased in ovarian cancer. A Differential expression of NEAT1 in normal samples and ovarian cancer samples in the GSE46169 dataset retrieved from the GEO database. B Expression of NEAT1 in ovarian cancer tissues and adjacent normal tissues determined by RT-qPCR, n = 68. C Expression of let-7 g in ovarian cancer tissues and adjacent normal tissues determined by RT-qPCR, n = 68. D Pearson correlation analysis of NEAT1 expression level and let-7 g expression level in clinical samples, n = 68. E Expression of NEAT1 in normal ovarian epithelial cell line IOSE80 and ovarian cancer cell lines ES2, A2780, SKOV3 and HO8910 determined by RT-qPCR. F, Expression of let-7 g in normal ovarian epithelial cell line IOSE80 and ovarian cancer cell lines ES2, A2780, SKOV3 and HO8910 determined by RT-qPCR. In figure A, B * p < 0.05 vs. adjacent normal tissues. In figure D, E, * p < 0.05 vs. IOSE80 cell line. The measurement data were expressed as mean ± standard deviation. Comparisons between two groups were conducted using paired t-test, while comparison between multiple groups were performed by one-way ANOVA followed by Tukey's post hoc test. Cell experiments were performed 3 times independently