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Fig. 5 | Cancer Cell International

Fig. 5

From: LINC00115 promotes stemness and inhibits apoptosis of ovarian cancer stem cells by upregulating SOX9 and inhibiting the Wnt/β-catenin pathway through competitively binding to microRNA-30a

Fig. 5

miR-30a can target SOX9 to inhibit maintenance and promote apoptosis of OCSCs. A, B Levels of miR-30a SOX9, CD133, CD44, NANOG and POU5F1 in OCSCs were detected by RT-qPCR and Western blot analysis; C. Cell apoptosis was measured by flow cytometry. VS the mimic-NC + vector-NC group, *p < 0.05, **p < 0.01; vs the miR-30a mimic + vector-NC group, # p < 0.05. Data in panels A and B were analyzed using one-way ANOVA and Tukey’s multiple comparison test. The experiment was performed in triplicate and data were expressed as means ± standard deviation

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Cancer Cell International

ISSN: 1475-2867

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