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Fig. 4 | Cancer Cell International

Fig. 4

From: ARHGAP10 inhibits the epithelial–mesenchymal transition of non-small cell lung cancer by inactivating PI3K/Akt/GSK3β signaling pathway

Fig. 4

Overexpression of ARHGAP10 altered morphology and inhibit EMT in NSCLC cells. a Confocal imaging of actin cytoskeleton stained with phalloidin-FITC presented cellular morphological and cytoskeleton reorganization in A549 and NCI-H1299 cells. Results indicated that actin cytoskeleton changes from disarranged actin to a bundled pattern. b, c EMT-related proteins E-cadherin, N-cadherin, vimentin and snail were detected by Western blot and immunofluorescence. (*p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001)

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