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Fig. 5 | Cancer Cell International

Fig. 5

From: RAMS11 promotes CRC through mTOR-dependent inhibition of autophagy, suppression of apoptosis, and promotion of epithelial-mesenchymal transition

Fig. 5

Knockdown of RAMS11 downregulated AKT/mTOR signalling by promoting AMPK pathway. Downregulation of RAMS11 significantly reduced the phosphorylation of AKT and mTOR and induced phosphorylation of AMPK in B–D HCT-116 and F–H SW480 cell. The data was shown as relative expression mean ± SEM compared to Dsi-NC group using β-actin as housekeeping gene. (*P < 0.05, and n = 4)

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Cancer Cell International

ISSN: 1475-2867

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