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Fig. 2 | Cancer Cell International

Fig. 2

From: Exosomes from cervical cancer cells facilitate pro-angiogenic endothelial reconditioning through transfer of Hedgehog–GLI signaling components

Fig. 2

Effect of cervical cancer exosomes on endothelial cell vascularization. A Representative phase-contrast photomicrographs (magnification—100×) of endothelial tubular networks in Matrigel after 6 h in HUVEC co-incubated with exosomes (50 μg/ml) of different cervical cancer cell lines (upper row). Lower panels show corresponding quantitative evaluation of images by ImageJ Angiogenesis Analyzer plugin for meshes, nodes and tubes. B Effect of cervical cancer exosomes on total angiogenic profile. Cumulative data on number of nodes, branches, branch length and meshes of a representative experiment out of three independent experiments. Values are represented as mean ± s.d. (indicated as error bar). *p value ≤ 0.05 with respect to untreated HUVEC control

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