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Fig. 1 | Cancer Cell International

Fig. 1

From: Downregulation of Tim-1 inhibits the proliferation, migration and invasion of glioblastoma cells via the miR-133a/TGFBR1 axis and the restriction of Wnt/β-catenin pathway

Fig. 1

Tim-1 was upregulated in glioblastoma tissues and cells. A Tim-1 mRNA expression in normal brain tissues (n = 15) and glioblastoma tissues (n = 76) were detected using qRT-PCR. The relative mRNA levels of Tim-1 in different cells are compared with HEB cells which was identified as 1.0. B Differences in Tim-1 expression in normal brain tissues (n = 15) and glioblastoma tissues (n = 76) were detected using immunohistochemical staining (the cells stained by brown)and H&E staining(× 5, × 10, × 40); C Tim-1 expression in human astrocyte HEB and human glioblastoma cell lines was detected using qRT-PCR and WB (n = 3). The relative protein levels of Tim-1 in different cells are compared with HEB cells which was identified as 1.0.* represented comparison with HEB, p < 0.05. Data were expressed as mean ± standard deviation, and t-test was used for comparisons between two groups. One-way ANOVA was used for comparisons between multiple groups, followed by t test with Bonferroni correction

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Cancer Cell International

ISSN: 1475-2867

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