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Fig. 5 | Cancer Cell International

Fig. 5

From: Downregulation of Tim-1 inhibits the proliferation, migration and invasion of glioblastoma cells via the miR-133a/TGFBR1 axis and the restriction of Wnt/β-catenin pathway

Fig. 5

Downregulated Tim-1 inhibited the proliferation, invasion and migration of glioblastoma cells, which could be reversed by downregulating miR-133a. A The expression of Tim-1 in U87 and U251 cells with Tim-1 knock-down were detected using qRT-PCR and WB; B The expression of miR-133a in U87 and U251 cells was detected using qRT-PCR; C The proliferation ability of U87 and U251 cells was detected by CCK-8 detection; D The invasion ability of U87 and U251 cells was detected by Transwell assay; E The migration ability of U87 and U251 cells was detected by wound healing test. *represented comparison with sh-NC, p < 0.05; + represented comparison with sh-Tim-1 + inhibitor NC, p < 0.05. n = 3. Data were expressed as mean ± standard deviation, and t-test was used for comparisons between two groups. One-way ANOVA was used for comparisons between multiple groups, comparison between two groups are followed by t test with Bonferroni correction

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Cancer Cell International

ISSN: 1475-2867

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