Fig. 3

Heatmap and functional enrichment analysis of methylation-driven genes in TCGA-UCEC. A Methylation values (β-values). The color change from green to red in the heatmap illustrates the trend from low to high methylation. B The expression of the methylation-regulated genes. The color change from green to red in the heatmap illustrates the trend from low to high expression. C The outer circle represents the methylation values (logFC) of methylated genes in each enriched GO (gene ontology) term: red dots on each GO term indicate upregulated genes, whereas blue dots indicate downregulated genes. The inner circle indicates the significance of GO terms (log10‐adjusted p values). D Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways