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Fig. 7 | Cancer Cell International

Fig. 7

From: Down-regulation of BCL2L13 renders poor prognosis in clear cell and papillary renal cell carcinoma

Fig. 7

BCL2L13 performs pro-apoptotic function in ccRCC cell line 786-0. A BCL2L13 expression is conspicuously lower in CAKi-1 cells and 786-0 cells, compared to HEK293T cells. B BCL2L13 expression is significantly lower in ccRCC tissues (upper row), compared to paracancerous tissues (lower row), when glomeruli (red arrows) are stained. Scale bar: 20 μm. CD BCL2L13 overexpression promotes apoptosis in 786-0 cells. 786-0 cells were transfected with indicated genes and treated with ABT-263 (5.5 μM) for 24 h, then subjected to western blotting (C) or flow cytometry (D). 786-0 cells treated with CCCP (50 μM) for 24 h were shown as a positive control (2nd lane of panel C). Results are shown as the mean ± s.e.m. A one-way analysis of variance (ANOVA) was performed by SPSS. * P < 0.05

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