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Fig. 4 | Cancer Cell International

Fig. 4

From: Ten-gene signature reveals the significance of clinical prognosis and immuno-correlation of osteosarcoma and study on novel skeleton inhibitors regarding MMP9

Fig. 4

Immunogenomic analysis between high- and low-risk group. A The enrichment levels of the 29-immune gene sets by ssGSEA score in each osteosarcoma sample. ESTIMATE method was performed to evaluate tumor purity, stromal score as well as immune score. B Comparison of 10-gene signature between high-risk and low-risk group in stromal score, immune score, estimate score and tumor purity. C Comparison of immune check point genes expression levels between high-risk and low-risk group. D Comparison of expression levels of HLA genes between high-risk and low-risk group. *P < 0.05, **P < 0.01, ***P < 0.0001, ns: no significant difference

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