Fig. 4

Immunogenomic analysis between high- and low-risk group. A The enrichment levels of the 29-immune gene sets by ssGSEA score in each osteosarcoma sample. ESTIMATE method was performed to evaluate tumor purity, stromal score as well as immune score. B Comparison of 10-gene signature between high-risk and low-risk group in stromal score, immune score, estimate score and tumor purity. C Comparison of immune check point genes expression levels between high-risk and low-risk group. D Comparison of expression levels of HLA genes between high-risk and low-risk group. *P < 0.05, **P < 0.01, ***P < 0.0001, ns: no significant difference