Fig. 1
From: Metformin exerts anti-AR-negative prostate cancer activity via AMPK/autophagy signaling pathway
Metformin played an inhibitory role in the growth and migration of human prostate cancer cells. a Cell viability was determined by CCK-8 test after DU145 and PC3 cells had been treated with metformin for 24, 48, and 72 h. b, c Clone ability of DU145 and PC3 cells was detected by colony formation assay with metformin treatment. d, e Cell proliferation was examined by EdU assay. Data are presented as the mean ± SD. *p < 0.05; **p < 0.01; ***p < 0.001 compared with the control group