From: A pancreas tumor derived organoid study: from drug screen to precision medicine
Tissue | Species | Matrix | Trans-plantation | Drug testing | Biomarker screen | References |
---|---|---|---|---|---|---|
Nomal pancreas PanIN PDAC | Murine Human | Embedded in Matrigel | Generation of PDAC and PanIN | Yes | Yes | [9] [24] [30] |
iPSCs PDAC | Human | Media and Matrigel | Generation primary tumor | Yes | Yes | [25] |
PDAC | Murine Human | Media and Matrigel | – | Yes | Yes | [34] [89] |
Neonatal tissue PDAC iPSCs | Murine Human | Air-liquid interface on Matrigel | Generation of PDAC | Yes | Yes | [32] |