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Fig. 3 | Cancer Cell International

Fig. 3

From: LRRK2 is a candidate prognostic biomarker for clear cell renal cell carcinoma

Fig. 3Fig. 3Fig. 3

LRRK2 differential expression and genomic alteration in ccRCC tissues compared with normal control. a LRRK2 expression level in both tumor and normal tissues based on TCGA-KIRC datasets; b LRRK2 expression level in ccRCC tissues and paired adjacent non-tumor tissue. c The gene expression, somatic mutation, copy number variation (CNV), and DNA methylation from USUC Xena databases. d The mutation sites of LRRK2 in ccRCC patients. e The LRRK2 putative copy-number alterations according to cBioPortal for Cancer Genomics. f Negative correlations between the expression of LRRK2 and DNA methylation. g The survival curves of 6 methylated sites of LRRK2 in ccRCC patients. ccRCC clear cell renal cell carcinoma, KIRC kidney renal clear cell carcinoma

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