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Table 2 KEGG pathway analysis of the hyper-DMGs

From: Aberrantly methylated-differentially genes and pathways among Iranian patients with colorectal cancer

ID Pathway description Gene count False discovery rate Matching proteins in network (labels)
5217 Basal cell carcinoma 12 5.79E−07 BMP2,FZD1,GLI3,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4340 Hedgehog signaling 11 1.25E−06 BMP2,GAS1,GLI3,IHH,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4340 Hedgehog signaling 11 1.25E−06 CTBP2,DKK1,FZD1,NFATC1,SFRP2,SFRP5,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4310 Wnt signaling 15 2.78E−05 CREB3L1,FZD1,GNAS,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4916 Melanogenesis 12 9.14E−05 BCL2,BMP2,COL4A2,CTBP2,FGF12,FGF3,FGFR1,FZD1,GLI3,IGF1R,JUP,PDGFRA,TCF7,TCF7L1,TGFB1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
5200 Pathways in cancer 22 0.00015 BMP2,FZD1,PPP2R2A,STK3,TCF7,TCF7L1,TGFB1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4390 Hippo signaling 14 0.000203 CAV1,FGF12,FGF3,FGFR1,FZD1,IGF1R,IGF2,SDC2,TGFB1,TWIST2,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
5205 Proteoglycans in cancer 17 0.000286 CDK14,IGF1R,IGFBP3,JUP,MEIS1,NGFR,NR4A3,PAX7,SIX1,TLX3,WNT16,WT1
5202 Transcriptional misregulation in cancer 12 0.01 BCL2,CREB3L1,CREB5,FGFR1,IGF1R,PDGFRA,TCF7,TCF7L1
5215 Prostate cancer 8 0.0177 AVPR1A,CACNA1I,CD38,GNAS,GRIN2A,GRIN2C,ITPKB,NOS1,PDE1B,PDGFRA,TACR1
4020 Calcium signaling 11 0.0474 CTBP2,DKK1,FZD1,NFATC1,SFRP2,SFRP5,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B
4340 Hedgehog signaling 11 1.25E−06 CREB3L1,FZD1,GNAS,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B