Table 2 KEGG pathway analysis of the hyper-DMGs
ID | Pathway description | Gene count | False discovery rate | Matching proteins in network (labels) |
|---|---|---|---|---|
5217 | Basal cell carcinoma | 12 | 5.79E−07 | BMP2,FZD1,GLI3,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4340 | Hedgehog signaling | 11 | 1.25E−06 | BMP2,GAS1,GLI3,IHH,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4340 | Hedgehog signaling | 11 | 1.25E−06 | CTBP2,DKK1,FZD1,NFATC1,SFRP2,SFRP5,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4310 | Wnt signaling | 15 | 2.78E−05 | CREB3L1,FZD1,GNAS,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4916 | Melanogenesis | 12 | 9.14E−05 | BCL2,BMP2,COL4A2,CTBP2,FGF12,FGF3,FGFR1,FZD1,GLI3,IGF1R,JUP,PDGFRA,TCF7,TCF7L1,TGFB1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
5200 | Pathways in cancer | 22 | 0.00015 | BMP2,FZD1,PPP2R2A,STK3,TCF7,TCF7L1,TGFB1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4390 | Hippo signaling | 14 | 0.000203 | CAV1,FGF12,FGF3,FGFR1,FZD1,IGF1R,IGF2,SDC2,TGFB1,TWIST2,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
5205 | Proteoglycans in cancer | 17 | 0.000286 | CDK14,IGF1R,IGFBP3,JUP,MEIS1,NGFR,NR4A3,PAX7,SIX1,TLX3,WNT16,WT1 |
5202 | Transcriptional misregulation in cancer | 12 | 0.01 | BCL2,CREB3L1,CREB5,FGFR1,IGF1R,PDGFRA,TCF7,TCF7L1 |
5215 | Prostate cancer | 8 | 0.0177 | AVPR1A,CACNA1I,CD38,GNAS,GRIN2A,GRIN2C,ITPKB,NOS1,PDE1B,PDGFRA,TACR1 |
4020 | Calcium signaling | 11 | 0.0474 | CTBP2,DKK1,FZD1,NFATC1,SFRP2,SFRP5,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |
4340 | Hedgehog signaling | 11 | 1.25E−06 | CREB3L1,FZD1,GNAS,TCF7,TCF7L1,WNT1,WNT16,WNT2,WNT3A,WNT5A,WNT6,WNT7B |