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Fig. 1 | Cancer Cell International

Fig. 1

From: NCK1-AS1 promotes the progression of melanoma by accelerating cell proliferation and migration via targeting miR-526b-5p/ADAM15 axis

Fig. 1

NCK1-AS1 is overexpressed in melanoma cells and boosts cell proliferation and migration in melanoma. A RT-qPCR was used to evaluate NCK1-AS1 expression in melanoma cell lines (A-375, M21, A-875, A2085 and M14) and normal control (HaCaT). B Knockdown efficiency of sh/NCK1-AS1 in the transfected melanoma cells with sh/NCK1-AS1#1/2/3 was assessed by RT-qPCR. CE The proliferative abilities of A-375 and M21 cells after the transfection of sh/NC or sh/NCK1-AS1#1/2 were assessed by CCK-8, colony formation and EdU assays. F, G The migratory abilities of the transfected melanoma cells with sh/NC or sh/NCK1-AS1#1/2 were examined by transwell migration and wound healing assays. *p  <  0.05, **p  <  0.01

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