Fig. 1

FAO Basics. After entering into the cell via fatty acid protein transporters, fatty acids are activated to acyl-CoA. The carnitine carnitine palmitoyltransferase system then transports acyl-CoA from cytoplasm into mitochondrial matrix for oxidation: CPT1 converts acyl-CoA into acylcarnitines and CPT2 converts acylcarnitine back into acyl-CoA for oxidation