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Fig. 2 | Cancer Cell International

Fig. 2

From: Fatty acid oxidation: driver of lymph node metastasis

Fig. 2

FAO and EMT. Some markers of EMT, such as Vimentin, Snail and E-cadherin are regulated by FAO. Vimentin and Snail are upregulated but E-cadherin is decreased, which display a start of cancer invasion. FAO is enhanced via the p-AMPK pathway owing to TGF-β1 expression activating TGF-β1/Smad signaling to boost EMT

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