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Table 3 Exosomal RNAs as biomarkers for Paca

From: The significance of exosomal RNAs in the development, diagnosis, and treatment of pancreatic cancer

RNA Type Molecules Origin Potential functions Refs.
miRNA miRNA‑21 Peripheral blood Early diagnosis/tumor stage/survival evaluation [116,117,118,119]
miRNA-210 Peripheral blood Early diagnosis/tumor stage [116]
miRNA-10b Peripheral blood Early diagnosis [117, 120]
miRNA-1246 Peripheral blood Early diagnosis [121]
miRNA-451a Peripheral blood Tumor stage/survival evaluation [122]
miRNA-222 Peripheral blood Tumor stage/survival evaluation [61]
miRNA-4525 Portal vein blood Recurrence prediction/survival evaluation [124]
miRNA-451a Portal vein blood Recurrence prediction/survival evaluation [124]
miRNA-21 Portal vein blood Recurrence prediction/survival evaluation [124]
miRNA-21 Pancreatic juice Early diagnosis [125]
miRNA-155 Pancreatic juice Early diagnosis [125]
miRNA-1246 Salivary Early diagnosis [126]
miRNA-4644 Salivary Early diagnosis [126]
lncRNA Sox2ot Peripheral blood Tumor stage/survival evaluation [77]
HULC Peripheral blood Early diagnosis [75]
CRNDE Peripheral blood Early diagnosis [136]
MALAT-1 Peripheral blood Early diagnosis [136]
circRNA PDE8A Peripheral blood Tumor stage/survival evaluation [78]
IARS Peripheral blood Tumor stage/survival evaluation [79]
mRNA WASF2 Peripheral blood Early diagnosis/tumor stage/ [139]
GPC1 Peripheral blood Early diagnosis/tumor stage/ [140]