Fig. 4

Knockdown of circDPP4 inhibits PCa tumor growth in vivo. A Tumor volume was monitored every week. B Representative images of tumors and quantification of tumor weights. C RT-qPCR analysis of circDPP4 expression levels in the tumor tissues. D Western blot analysis of cyclin D1 protein expression levels in the tumor tissues. E H&E staining and immunohistochemistry (IHC) analysis of Ki-67 protein in the tumor tissues. *P < 0.05 vs. sh-NC group