LncRNA HAND2-AS1 exerts anti-oncogenic effects on bladder cancer via restoration of RARB as a sponge of microRNA-146

Table 1 The relationship between HAND2-AS1 expression and clinical characteristics of bladder cancer

Variables	Description	No. of patient	HAND2-AS1 expression		χ²	P-value
Variables	Description	No. of patient	Low	High	χ²	P-value
Gender	Male	22	16	6	0.0253	0.873
Gender	Female	10	7	3	0.0253	0.873
Age (years)	< 60	8	6	2	0.0515	0.820
Age (years)	≥ 60	24	17	7	0.0515	0.820
Tumor size	≤ 3 mm	10	5	5	3.4431	0.063
Tumor size	> 3 mm	22	18	4	3.4431	0.063
Depth of invasion	Tis-T1	13	6	7	7.1656	0.007*
Depth of invasion	T2–T4	19	17	2	7.1656	0.007*
Nodes	N0	18	8	10	1.24494	0.264
Nodes	N1–N3	14	9	5	1.24494	0.264
Metastasis	M0	21	12	9	0.396028	0.529
Metastasis	M1	11	5	6	0.396028	0.529
Grades	G1	9	4	5	4.6608	0.030*
Grades	G2–G3	23	19	4	4.6608	0.030*
Stages	Stage 0–2	13	9	10	0.9579	0.327
Stages	Stage 3–4	19	12	7	0.9579	0.327

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