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Fig. 8 | Cancer Cell International

Fig. 8

From: Integrative analysis the characterization of peroxiredoxins in pan-cancer

Fig. 8

PRDX6 promotes bladder cancer cell proliferation via JAK2-STAT3 pathway. A The GSEA plot of JAK/STAT pathway between PRDX6 high and low group. B, C Western blot was used to test JAK2, p-STAT3 and STAT3 protein both in T24 cells (B) and TCCSUP cells (C). DG To test whether PRDX6 regulate the cell growth via JAK2-STAT3 pathway, western blot assays and CCK8 were performed on T24 cells (D, F) and TCCSUP cells (E, G) transfected with control, shPRDX6, oeSTAT3, shPRDX6 + oeSTAT3. HK Colony formation were performed on T24 cells (H, I) and TCCSUP cells (J, K) transfected with control, shPRDX6, oeSTAT3, shPRDX6 + oeSTAT3. *P < 0.05, **P < 0.01

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