Fig. 1From: Anti-cancer properties of quercetin in osteosarcomaFactors involved in the pathogenesis of osteosarcoma can be divided into two types: environmental factors and endogenous factors. Endogenous factors include some predisposing syndromes (such as Li-Fraumeni syndrome), changes in cell signaling pathways, and abnormal expressions of proteins and RNAs. Meanwhile, environmental factors are mainly radiation and chemical agentsBack to article page