Fig. 2

The development of the CRRS model based on the LASSO algorithm. A Ten-fold cross-validations to tune the parameter selection in the LASSO model. The two dotted vertical lines are drawn at the optimal values by minimum criteria (left) and 1 − SE (standard error) criteria (right). B LASSO coefficient profiles of the candidate genes for CRRS construction. C The distribution of risk score, recurrence status, and gene expression panel in four cohort