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Fig. 4 | Cancer Cell International

Fig. 4

From: lncRNA DLEU2 promotes gastric cancer progression through ETS2 via targeting miR-30a-5p

Fig. 4

DLEU2 acts as a ceRNA targeting ETS2 via miR-30a-5p. A Up: The sequences of miR-30a-5p, wide type of DLEU2 (WT), and mutated lncRNA DLEU2 (Mut). Down: The expression levels of luciferase in AGS cells transfected with wild-type (WT) or mutated (Mut) DLEU2 reporters plus miR-30a-5p mimic or miR-NC were determined. B Up: The sequences of miR-30a-5p, wide type of ETS2 (WT), and mutated ETS2 (Mut). Down: The expression levels of luciferase in AGS cells transfected with wild-type (WT) or mutated (Mut) ETS2 reporters plus miR-30a-5p mimic or miR-NC were determined. C The expression of ETS2 in AGS and MKN-45 cells transfected with si-DLEU2, and in HGC-27 cells transfected DLEU2 overexpression plasmid (DLEU-OE). D The expression of ETS2 in GC tissues and adjacent normal ovarian tissues was evaluated via immunohistochemistry. *P < 0.05

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