Table 2 Correlation between serum exosomal miR-3913-5p expression levels in patients with NSCLC and their clinicopathological characteristics. (* p < 0.05)

Age(years), Median

0.714

 < 60

32

25

7

 ≥ 60

31

23

8

Gender

0.427

 Male

28

20

8

 Female

35

28

7

Smoking history

0.321

 Never smoking

48

38

10

 Now/once smoking

15

10

5

ECOG Score

0.064

 0–1

52

42

10

 ≥ 2

11

6

5

Primary tumor

0.64

 ≤ 4 cm

18

13

5

 > 4 cm

45

35

10

TNM

0.045*

 I–IVA

24

15

9

 IVB

39

33

6

PLT

0.024*

 Low(≤ 146)

13

13

0

 High(> 146)

50

35

15

LDH

0.427

 Low(≤ 199)

28

20

8

 High(> 199)

35

28

7

CEA

0.045*

 Low(≤ 8.605)

24

15

9

 High(> 8.605)

39

33

6

Distant metastasis

0.049*

 No

17

10

7

 Yes

46

38

8

Contralateral lung metastasis

0.434

 No

24

17

7

 Yes

39

31

8

Pleura metastasis

0.414

 No

32

23

9

 Yes

31

25

6

Bone metastasis

0.03*

 No

23

14

9

 Yes

40

34

6

Brain metastasis

0.112

 No

35

24

11

 Yes

28

24

4